The First FDA-Approved Injectable for Improving Patient Skin Hydration and Smoothness
Skinvive by Juvéderm is the first FDA-approved hyaluronic acid microdroplet injectable designed to improve skin smoothness and hydration — not add volume. Unlike traditional fillers that reshape or lift facial tissue, Skinvive works just beneath the skin’s surface to deliver deep, lasting moisture at the dermal level. The result is a refreshed, radiant, naturally hydrated complexion often described as “glass skin.” Approved on May 11, 2023, it remains the only injectable of its kind cleared specifically for cheek skin smoothness in adults 21 and older.
Why Offer It
- Deep Dermal Hydration – Skinvive retains up to 1,000 times its weight in water, increasing hydration at the dermal layer for a visibly plumper, dewier surface that topical serums cannot replicate — making it a strong addition to any skin quality protocol.
- Natural, Subtle Outcomes – Because it targets skin quality rather than volume, Skinvive improves smoothness and radiance without altering facial contours, making it an easy recommendation for patients hesitant about looking “filled.”
- Efficient Chair Time – The procedure takes approximately 15 minutes, with most patients returning to daily activities immediately. Mild redness or swelling at the injection site typically resolves within 7 days.
- High Patient Satisfaction – Clinical studies show 83% of participants were satisfied with their skin at six months post-treatment, supporting strong retention and repeat visit potential.
- FDA-Approved Safety Profile – As the first and only microdroplet injectable approved for skin smoothness, Skinvive has been rigorously evaluated for both efficacy and safety across all Fitzpatrick skin types.
What Makes It Different
Most dermal fillers are engineered to restore volume, contour cheeks, or fill deep wrinkles, using high-viscosity gels injected deep into facial tissue. Skinvive is built for an entirely different clinical purpose.
- Microdroplet Injection Technique – Rather than deep tissue placement, Skinvive uses an intradermal microdroplet technique, distributing tiny deposits of hyaluronic acid (HA) across the cheeks to hydrate without bulking or altering contours.
- Skin Booster Formulation – With a lower HA concentration (~12 mg/mL) and softer rheological profile than volumizing fillers, Skinvive is specifically formulated to improve skin texture, softness, and natural moisture retention — not projection or lift.
- Glass Skin Effect – By rehydrating the dermis from within, Skinvive achieves the coveted dewy, translucent appearance patients describe as glowing and healthy — a differentiating outcome that complements your existing filler and neuromodulator offerings.
Procedure Overview
- Consultation — Review the patient’s medical history, aesthetic goals, and skin condition to confirm Skinvive is appropriate. Assess for any contraindications, allergies, or relevant medical conditions.
- Microdroplet Injection — HA is injected intradermally in a grid pattern across the cheeks using fine-gauge needles. The formula includes 0.3% lidocaine to minimize patient discomfort. A full treatment typically requires two syringes.
- Hydration Enhancement — Once injected, the crosslinked HA attracts and retains moisture within the dermis, smoothing texture, reducing dryness, and producing a visibly hydrated, glowing appearance that develops fully over the first few weeks.
Treatment Details
- Active Ingredient: Crosslinked hyaluronic acid with 0.3% lidocaine
- Treatment Time: Approximately 15 minutes
- Target Area: Cheeks (FDA-approved indication)
- Patient Eligibility: Adults 21 and older
- FDA Approval: May 11, 2023
- Duration of Results: Up to six months
- Maintenance Schedule: Repeat sessions every 6–9 months to sustain results
- Typical Pricing: $600–$700 per session (varies by market and practice)
Ideal Patient Profile
Consider Skinvive for patients who:
- Are adults over 21 seeking improved skin hydration and smoothness without volume changes
- Have plateaued with topical skincare and want deeper, structural hydration
- Are pursuing the “glass skin” or “jello skin” aesthetic — a naturally radiant, healthy look
- Want to enhance skin texture while keeping natural facial contours intact
- Are already receiving other treatments — Skinvive integrates well alongside fillers, Botox, laser treatments, and chemical peels, and can enhance overall outcomes
If your patient wants skin that looks more hydrated, smooth, and refreshed without appearing “done,” Skinvive is a strong clinical fit.
Add Skinvive to Your Practice
Skinvive by Juvéderm offers a clinically differentiated, high-satisfaction treatment for patients seeking skin quality improvement without volumization. With minimal chair time, a strong safety profile, and results lasting up to six months, it is a natural complement to existing aesthetic protocols.
Schedule a rep consultation or training session to learn how to integrate Skinvive into your practice and optimize patient outcomes.
Results may vary. Administer only after appropriate training and patient evaluation. Loyalty program points may be available through select provider programs — confirm with your Allergan representative.















